August - Sept 2009

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BREAKING NEWS!!!

 

FYI-PAPANICOLAOU CORPS AUGUST-SEPTEMBER, 2009
(Please note-- all of the physicians listed are with the University of Miami/ Miller School of Medicine) - Source—Communications Dept.

Pap President, Tutsie Lipkin, has received a letter of thanks from Jerry Goodwin, M.D., F.A.C.S., Director of Sylvester Comprehensive Cancer Center, for our generous gift of $3,000,000 this past year. An example of our gift, designated for cancer research, has been the recruitment of a renowned physician and researcher to lead the adult stem cell transplant program. This work promises to help us develop better understanding of how the immune system reconstitutes itself after stem cell transplantation, leading to better patient outcomes. Pap Corps members can be proud of their accomplishments.

Some 650,000 people are alive today because of the advances in cancer prevention, detection and treatments over the past 15 years, according to a 2009 cancer report.

Ralph Sacco, M.D., professor and chairman of neurology is quoted in an article about the effectiveness of graduated compression stockings. These stockings not only fail to prevent deep vein thrombosis after stroke, but also damage the skin.

Ray Hershberger, M.D., professor of medicine and associate chief of the Cardiovascular Division is the principal investigator of a project working to identify the genetic cause of cardiomyopathy and heart failure. The inherited heart muscle disease results in an enlargement of the heart and a weakening of the hearts pumping action.

Sara Czaja, M.D., professor of psychiatry and behavioral sciences and co-director of the Center on Aging has joined other researchers in developing a new screening system that helps provide intervention for caregivers of dementia patients.

Zapping away abnormal precancerous cells in the throat may lower the risk of later developing esophageal cancer. This procedure may work on some patients with Barretts esophagus which occurs when stomach acid backs up in the throat (heart burn).

A multicenter research team has announced encouraging results for an experimental therapy using elements of the body’s immune system to improve cure rates for children with neuroblastoma, a cancer of the nervous system. After treatment the survivors are still fit regardless of the treatment, age or body mass.

Cutting back on carbohydrates appears to slow the growth of prostate tumors, even if pounds aren’t lost.

While cancer cells need genetic mutations to thrive, a new study finds that they also rely heavily on normal proteins to deal with stress and maintain their deviant state.

An experimental drug derived from cottonseed shows promise in treating the recurrence of glioblastoma multiforme, widely considered the most lethal brain cancer.

Lee Sanders, M.D. associate professor of pediatrics found that many parents in South Florida mistakenly use over the counter cough and cold medicines to babies under age 2.

Taking aspirin reduces heart attack risk in people with no previous history of vascular disease but increases the risk of internal bleeding.

One month after mandating stricter warning labels about the risk of liver damage from the painkiller acetaminophen, regulators are contemplating even tougher standards.

Stimulant chewing gum can be dangerous if used excessively by children and teens.

Scientists are exploring the possibility that drugs that affect the immune system might one day serve as potent weapons to fight the flu, even the swine flu that is currently circulating around the globe.

A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials. Aerosol delivery targets the lungs specifically and represents a noninvasive alternative.

Despite a steady decline in colorectal cancer rates in the United States in the past two decades, new research indicates that the disease is actually on the upswing among people under 50, especially those in their 20’s. This age group does not routinely get screening and clinicians should be aware of the symptoms when they occur in this age group.

Alexandre Rocha Abreu, M.D., assistant professor of medicine in the Division of Pulmonary, Critical Care and Sleep medicine spoke about excessive time spent playing computer games leaving some people sleep-deprived.

Bruno Gallo, M.D., assistant professor of clinical neurology discussed the completion of patient implants in a pivotal clinical study of deep brain stimulation for the symptomatic treatment of Parkinson’s disease. Dr. Gallo is an investigator in the study using Libra and LibraXP neurostimulators, which are surgically, implanted devices that generate mild electrical pulses to targeted areas of the brain.

Clinton Wright, M.D., associate professor of neurology, agrees with the theory that there is potential increased risk for cognitive impairment in older people who take common over-the counter drugs for pain, cold symptoms or sleeplessness. Drug mixing can be fatal to the senior population as well.

Intensely lowering blood sugar in the early years of diabetes may reduce the chance of heart problems and premature death. However, the same aggressive treatment does not appear to help as much in long-time type 2 diabetics.

Older adults with mid cognitive impairment or Alzheimer’s disease have a shorter life span than other older adults; however, race has no bearing on life expectancy.

One quarter of supplements tested by an independent company over the last decade have had some sort of problem. Some contained contaminants, while others had contents that did not match label claims.

Researchers have found links between an individual’s genetics and their response to treatment with chemotherapy. The findings show how a genetic variant located in the SOD2 gene may affect how a person responds to the chemo drug cyclophosphamide. This drug is used in the treatment of breast and other cancers.

For most patients with acute myeloid leukemia (AML) who come out of remission, donor stem cells appear to offer the best shot at survival.

Scientists have discovered a molecular mechanism that plays a pivotal role in controlling cancer growth in the brain. The discovery could be the basis for potentially effective therapies for the treatment of brain metastasis.

W. Garrard Goodwin, M.D, director of Sylvester, and Pascal J. Goldschmidt, M.D., senior vice president for medical affairs and dean, presented State Senator Ted Deutch with an award, thanking him for his support of the tobacco surcharge which will help yield millions of dollars in cancer research funding at Sylvester.

Researchers have zeroed in on the cause of a deadly type of ovarian cancer, a finding that could lead to successful treatment of the rare granulose cell tumors.

Men with moderately advanced prostrate cancer who get hormone-blocking drugs after radiation therapy do better when the drug treatment is continued for two or more years after an initial six month regimen. Longer hormone treatments may improve the outlook for prostate cancer patients.

UM/Miller School of Medicine has embarked on a partnership with Microsoft to determine if computer technology can help manage patients with chronic diseases. A pilot project has been started to help diabetics in Overtown learn how to manage their disease. This can perhaps change the future of primary care.

The World Health Organization raised its flu warning to the highest level, declaring the first flu pandemic in 41 years.

The nicotine in cigarette smoke may promote insulin resistance and lead to a condition known as prediabetes.

Two new studies suggest that chronic poor sleep can actually boost your odds for dying prematurely, while another study finds that more than half of older Americans aren’t getting the recommended eight hours of slumber.

Eating a diet rich in carbohydrates that boost blood sugar levels---foods such as cornflakes or white bread---may hamper the functioning of your blood vessels and raise your risk of developing cardiovascular disease.

Gaetano Ciancio, M.D., professor of surgery and urology, has incorporated liver transplantation techniques for the resection of large renal tumors, with or without, inferior vena cava involvement.

Scientists have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. The cancer cells actually eat themselves.

Scientists in Europe are reporting “convincing evidence” that marijuana smoke damages the genetic material of DNA in ways that could increase the risk of cancer.

A new study suggests that cancer may be stopped by delivering replacement therapy, known as microRNAs, control genes commonly lost in cancerous tumors

Nicotine receptors drive the urge to smoke and increase susceptibility to lung cancer. In a study of mice with lung cancer, a treatment that target nicotine receptors more than doubled the animal’s survival time.

Stimulant medications commonly prescribed to treat attention deficit hyperactivity disorder (ADHD) is associated with an increased risk of sudden death, but these deaths are rare.

The FDA has requested that asthma drugs get “precaution” labeling for possible psychiatric side effects. Some of these drugs are Singular, Accolate and Zyflo.

The American Academy of Pediatrics wants doctors to take an active role in preventing bullying in schools and violence among dating teenagers and is giving physicians tips for doing that.

David Zambrana, chief nursing officer at UM Hospital has been named Chief Operating Officer of the 560 bed flagship hospital of UHealth.

Naomi Prever - Vice President of Education